Related Experiment Video
Updated: Sep 13, 2025
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Radiological progression of pneumoconiosis cases over a 5-year follow-up and contributing factors: a retrospective
M Acun Pinar1, G Sari2, A Koyuncu2
1Department of Pulmonary Medicine, Division of Occupational Diseases, Gazi Yaşargil Training and Research Hospital, Diyarbakır, 21070, Türkiye.
Background:
Pneumoconiosis remains a significant cause of morbidity and mortality worldwide and there is no known effective treatment for the disease. Therefore, preventing progression of pneumoconiosis is crucial.
Aims:
This study aims to evaluate the radiological progression of pneumoconiosis cases and identify factors influencing progression over a 5-year follow-up period.
Methods:
The study included pneumoconiosis cases that presented to the occupational diseases' clinic of a teaching and research hospital between 2014 and 2024, and for whom radiological imaging and functional assessments were available both at the time of initial diagnosis and at the fifth year. The chest X-rays of patients at initial diagnosis and at 5 years were evaluated by two ILO pneumoconiosis readers for radiological progression. Factors affecting progression were examined using univariate and multivariate logistic regression analyses. A P-value of <0.05 was considered statistically significant.
Results:
Of the 759 patients, 131 cases with control evaluations available at the fifth year were included in the study. Radiological progression was detected in 68 cases (52%). Significant differences between the progression and non-progression groups were found for the following factors: age, smoking status, occupational groups, type of pneumoconiosis, pneumoconiosis severity and the dominant small opacity size. Logistic regression analysis identified smoking and working in the ceramics industry as independent risk factors for the development of progression.
Conclusions:
In the follow-up, more than half of the pneumoconiosis cases showed progression. Identifying factors associated with progression will be beneficial in reducing morbidity and mortality related to the disease.
Related Concept Videos
01:27Pneumothorax-II
Clinical Manifestations:
01:30Pneumonia III: Complications and Assessment
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
01:22Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
01:20COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...