Related Experiment Video
Updated: Sep 13, 2025
06:26
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
485
Mortality in acute type A aortic dissection - A systematic review based on contemporary registries
Diana-Cristina Matei1,2, Cornel Robu1,2, Celia Georgiana Ciobanu1,2
1Emergency Institute for Cardiovascular Diseases "Prof. Dr. C.C. Iliescu", Street Fundeni 258, Bucharest, Romania.
Summary
Early mortality in acute type A aortic dissection (ATAAD) is high and varies significantly across registries. Standardizing reporting is crucial for better risk assessment and equitable patient care.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Acute type A aortic dissection (ATAAD) is a critical cardiovascular emergency.
- High early mortality rates present significant clinical and organizational challenges.
- Large observational registries provide real-world outcome data.
Purpose of the Study:
- To synthesize and compare early mortality rates in ATAAD patients from national and multicenter registries.
- To analyze trends and variations in mortality outcomes.
Main Methods:
- A systematic literature search was performed in PubMed, Google Scholar, and Cochrane Library.
- Included registry-based studies published within the last 10 years.
- Extracted data on in-hospital, 30-day, operative, or 48-hour mortality, study characteristics, demographics, and risk factors.
Main Results:
- Twenty registries including 77,267 patients were analyzed.
- In-hospital mortality ranged from 5% to 29% across 13 registries.
- Variations in outcome definitions and inclusion criteria hindered direct comparison.
Conclusions:
- Early mortality for ATAAD remains high and inconsistent among registries.
- Enhanced global registry participation and standardized reporting are vital.
- These improvements will aid risk stratification, clinical decision-making, and equitable care.
More Related Videos
Related Concept Videos
01:15Aortic Regurgitation I: Introduction
38
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
38
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
24
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
24
01:22Aortic Regurgitation II: Clinical Features and Diagnostic Tests
55
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
55
01:25Aortic Regurgitation III: Medical Management
44
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
44
01:30Aneurysm I: Introduction
26
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
26
01:17Aortic Regurgitation IV: Nursing Management
55
A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
55