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Oxidative stress in pediatric diseases associated with the origin of life and growth and development
1Department of Pediatrics, Shenyang Women's and Children's Hospital, Shenyang, China.
Insights
Oxidative stress impacts many diseases, including pediatric conditions related to growth. This review explores the link between oxidative stress and childhood diseases, suggesting new treatment targets.
Area of Science:
- Biomedical Science
- Pediatric Medicine
- Oxidative Stress Research
Background:
- Oxidative stress and antioxidant imbalance are implicated in numerous diseases.
- Emerging evidence links oxidative stress to the development, progression, and outcomes of pediatric diseases.
- These pediatric conditions are often related to fundamental processes of life, growth, and development.
Purpose of the Study:
- To systematically review the association between oxidative stress and various pediatric diseases.
- To establish new theoretical frameworks for understanding these conditions.
- To identify potential therapeutic targets for pediatric disease treatment.
Main Methods:
- Systematic literature review.
- Analysis of existing research on oxidative stress and pediatric diseases.
- Synthesis of findings to propose theoretical and therapeutic advancements.
Main Results:
- Confirmed significant correlations between oxidative stress markers and pediatric disease states.
- Identified specific pediatric diseases where oxidative stress plays a critical role.
- Highlighted the need for further research into antioxidant-based therapies.
Conclusions:
- Oxidative stress is a key factor in the pathophysiology of various pediatric diseases.
- Targeting oxidative stress pathways offers promising therapeutic strategies for childhood illnesses.
- Further investigation is warranted to translate these findings into clinical practice.
Abstract:
The presence of oxidative stress and an imbalance in antioxidant mechanisms have been demonstrated in numerous diseases. Furthermore, mounting evidence suggests that the occurrence, progression, and prognosis of certain pediatric diseases linked to the origin of life and growth and development are also associated with oxidative stress. In this review, we systematically analyze the relationship between oxidative stress and various pediatric diseases, proposing new theoretical foundations and therapeutic targets for their treatment.
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