Oxidative stress in pediatric diseases associated with the origin of life and growth and development

Bo Zheng1, Jianhua Fu2

  • 1Department of Pediatrics, Shenyang Women's and Children's Hospital, Shenyang, China.

Insights

Oxidative stress impacts many diseases, including pediatric conditions related to growth. This review explores the link between oxidative stress and childhood diseases, suggesting new treatment targets.

Area of Science:

  • Biomedical Science
  • Pediatric Medicine
  • Oxidative Stress Research

Background:

  • Oxidative stress and antioxidant imbalance are implicated in numerous diseases.
  • Emerging evidence links oxidative stress to the development, progression, and outcomes of pediatric diseases.
  • These pediatric conditions are often related to fundamental processes of life, growth, and development.

Purpose of the Study:

  • To systematically review the association between oxidative stress and various pediatric diseases.
  • To establish new theoretical frameworks for understanding these conditions.
  • To identify potential therapeutic targets for pediatric disease treatment.

Main Methods:

  • Systematic literature review.
  • Analysis of existing research on oxidative stress and pediatric diseases.
  • Synthesis of findings to propose theoretical and therapeutic advancements.

Main Results:

  • Confirmed significant correlations between oxidative stress markers and pediatric disease states.
  • Identified specific pediatric diseases where oxidative stress plays a critical role.
  • Highlighted the need for further research into antioxidant-based therapies.

Conclusions:

  • Oxidative stress is a key factor in the pathophysiology of various pediatric diseases.
  • Targeting oxidative stress pathways offers promising therapeutic strategies for childhood illnesses.
  • Further investigation is warranted to translate these findings into clinical practice.

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