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Updated: Sep 13, 2025

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Postoperative Pain Management in the US vs Low-and-Middle-Income Countries by US Surgeons
Matthew S Linz1, Fatemeh P Parvin-Nejad2, Nivetha Srinivasan3
1Rutgers New Jersey Medical School, Newark, New Jersey USA.
US surgeons prescribe significantly more opioids after surgery compared to when they operate abroad. This highlights a need to reduce opioid overprescription in the US and promote non-opioid pain management.
Area of Science:
- Global Surgery
- Pain Management
- Public Health
Background:
- Opioid overprescription persists in the US despite the ongoing opioid epidemic.
- Prescribing patterns of US surgeons during international short-term surgical trips are not well understood.
- This study compares postoperative opioid prescribing by US surgeons in the US versus during surgical trips to low- and middle-income countries (LMICs).
Purpose of the Study:
- To compare postoperative opioid prescribing practices between US and LMIC patients.
- To identify disparities in pain medication management.
- To inform strategies for reducing opioid overreliance in surgical care.
Main Methods:
- Retrospective chart review of adult patients undergoing open inguinal hernia repair (2013-2019).
- Comparison of opioid and non-opioid pain medication prescriptions within 24 hours of surgery and at discharge.
- Analysis of demographic and perioperative characteristics.
Main Results:
- 76.0% of US patients received opioids postoperatively, compared to 19.4% of LMIC patients (p<0.00001).
- US patients received a median of 8.7 mg oral morphine equivalents (OMEs), while LMIC patients received 0 mg OMEs (p<0.0001).
- A significant difference in opioid prescribing was observed between the US and LMICs.
Conclusions:
- US surgeons prescribe substantially higher quantities of opioids postoperatively than when operating in LMICs.
- There is significant potential to reduce opioid prescribing in the US surgical settings.
- Increased utilization of non-opioid pain medications should be encouraged to combat opioid overprescription.
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