Physiological Reconstruction for Moderate-Severe Pelvic Organ Prolapse: A Multicenter Retrospective Self-Controlled...

Area of Science:

• Urogynecology
• Pelvic Floor Surgery
• Female Pelvic Medicine

Background:

• Pelvic organ prolapse (POP) affects many women, impacting quality of life.
• Current treatments aim to restore pelvic anatomy and function.

Purpose of the Study:

• To evaluate the clinical efficacy and safety of physiological reconstruction for moderate to severe POP.
• To assess the impact of this surgical technique on anatomical support and patient-reported outcomes.

Main Methods:

• A retrospective, self-controlled multicenter study involving 517 women undergoing physiological reconstruction.
• 364 women with POP-Q stage ≥3 were analyzed, with 330 followed for 2 years.
• Standardized outcome measures including POP-Q, PFDI-20, PFIQ-7, and PISQ-12 were used.

Main Results:

• Significant improvements in POP-Q scores were observed at 6 months, 1 year, and 2 years post-surgery (P < 0.001).
• All quality of life measures showed statistically significant improvements throughout the follow-up period.

Conclusions:

• Physiological reconstruction, particularly with modified anterior pelvic floor mesh, restores the physiologic axis and vaginal shape.
• This technique is effective for repairing the pelvic fascia tendon arch and is safe for severe POP cases.