Reversible go-no go deficits in a case of frontal lobe tumor

A 50-year-old woman had been treated for a psychiatric disorder for three years. Findings during the elementary neurological examination were essentially normal. However, a computed tomographic scan revealed a large meningioma in the falx involving the medial aspects of the frontal lobes bilaterally. Neuropsychological examination demonstrated deficits in complex attentional tasks and also many errors of commission in the go-no go test. Following surgical excision of the tumor, her go-no go performance became normal. This patient shows that damage to the medial frontal lobe can cause deficits in go-no go performance, and that these deficits can be reversible following resolution of the lesion.