Related Experiment Video
Updated: Sep 13, 2025

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
Cognitive dysfunction and depression in chemotherapy patients: a cross-sectional study from Turkey
Elif Dinler1, Deniz Kocamaz2, Mürşide Özpineci3
1Department of Physiotherapy and Rehabilitation, Hasan Kalyoncu University, Faculty of Health Science, Gaziantep, Türkiye. elif.dokunlu@hku.edu.tr.
Objective:
This study investigates the relationship between cognitive function and depression in cancer patients receiving chemotherapy.
Methods:
A cross-sectional study design was employed, involving 80 cancer patients undergoing chemotherapy. Data were collected using the Socio-Demographic Information Form, the Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog), and the Beck Depression Inventory (BDI). Assessments were conducted prior to the second cycle of chemotherapy.
Results:
Among participants, 72.8% were female and 47.5% aged 40-50. Moderate depressive symptoms were most common (45%). Cognitive dysfunction was inversely correlated with depression (r = -0.525, p < 0.001). Low income significantly predicted lower cognitive scores (p = 0.01).
Conclusion:
Chemotherapy patients exhibit cognitive decline and elevated depression levels. Socioeconomic status exacerbates these effects. Psychosocial interventions should be integrated into oncological rehabilitation.
Related Concept Videos
Depression: Overview
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

