Highly stable benzonitrile functionalized covalent organic framework coating for solid-phase microextraction of...

Area of Science:

• Analytical Chemistry
• Materials Science
• Environmental Science

Background:

• Hydroxyphenyl esters (PBs) are environmental contaminants requiring sensitive detection methods.
• Solid-phase microextraction (SPME) is a widely used technique for sample preparation.
• Development of novel, high-performance SPME coatings is crucial for improving analytical sensitivity and efficiency.

Purpose of the Study:

• To synthesize and characterize a mesoporous benzonitrile functionalized covalent organic framework (TpBD-CN-COF).
• To evaluate TpBD-CN-COF as a novel SPME fiber coating for the extraction of six PBs.
• To develop and validate an analytical method for PB determination in aqueous samples using GC-FID.

Main Methods:

• Synthesis of mesoporous TpBD-CN-COF material.
• Fabrication of SPME fibers coated with TpBD-CN-COF.
• Optimization of extraction parameters (time, temperature, pH, stirring speed).
• Analysis of extracted PBs using gas chromatography-flame ionization detector (GC-FID).

Main Results:

• The TpBD-CN-COF fiber coating exhibited excellent extraction performance for PBs, with an enrichment factor twice as high as TpBD-COF.
• The method achieved a wide linear range (0.06-500 μg L⁻¹), low limits of detection (0.003-0.042 μg L⁻¹), and good reproducibility (RSDs < 8.6%).
• The developed analytical method was successfully applied to detect PBs in cosmetics and environmental water samples with satisfactory recoveries (85.14-107.67%).

Conclusions:

• Mesoporous TpBD-CN-COF is a highly effective SPME coating material for the sensitive determination of PBs.
• The developed SPME-GC-FID method offers a robust and reliable approach for PB analysis in complex matrices.
• This novel material and method hold significant potential for environmental monitoring and quality control applications.