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Wound-Healing Properties of Henna in Pilonidal Sinus Surgery: A Randomized Study
Seyed A Khosravi1, Mohammad Kamalinejad2, Seyed M Javadi3
1From the Department of Traditional Persian Medicine, School of Persian Medicine, Shahed University, Tehran, Iran.
Indian Journal of Dermatology
|July 31, 2025
Summary
Lawsonia inermis extract (LIE) ointment significantly improved wound healing in pilonidal sinus surgery patients. This natural treatment reduced wound size and volume, potentially lowering post-operative complications.
Area of Science:
- Dermatology
- Surgical Wound Healing
- Phytomedicine
Background:
- Pilonidal sinus (PS) surgery often leads to significant post-operative wound complications and morbidity.
- Accelerating wound healing is crucial for minimizing these complications.
- Lawsonia inermis (henna) extract has demonstrated wound-healing properties.
Purpose of the Study:
- To evaluate the efficacy of Lawsonia inermis extract (LIE) ointment in promoting wound healing after pilonidal sinus surgery.
- To compare LIE's effectiveness against standard treatments like phenytoin and a negative control (eucerin).
Main Methods:
- A randomized, double-blind, controlled clinical trial was conducted with 60 patients.
- Participants were divided into three groups: LIE ointment, phenytoin, and eucerin.
- Wound dimensions (length, depth, volume) were measured on days 7, 14, and 28 post-surgery.
Main Results:
- LIE ointment significantly reduced wound length and depth compared to phenytoin and eucerin after two weeks.
- Wound volume was substantially lower in the LIE-treated group (P < 0.05).
Conclusions:
- Lawsonia inermis extract (henna) possesses significant wound-healing properties.
- LIE ointment effectively enhances the healing of post-operative pilonidal sinus wounds.
- This can potentially reduce infection risk and improve patient outcomes.
