Preparation of new modified pyrogallol vinyl monomer and its antimicrobial and antioxidant properties

Biomaterials are widely applied. However, their application is limited as they cannot be processed using conventional industrial fabrication methods, such as extrusion, injection molding, or polymerization. Therefore, pyrogallol (PG), a functional biomaterial, was methacrylated using glycidyl methacrylate (GMA) through a simple ring-opening reaction. The introduction of GMA into the backbone of PG led to the synthesis of methacrylated pyrogallol (PGMC) vinyl monomers, which have high thermal stability, potent antimicrobial properties, and strong antioxidant activity. In addition, the chemical modification of PG led to the introduction of an additional reactive group (methacrylate group), making PGMC monomers processable for industrial purposes. Therefore, PGMC monomers can be used as strong bioactive agents for conventional heat-induced fabrication processes or for copolymerization with other monomers.

The online version contains supplementary material available at 10.1007/s13197-025-06228-9.