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Bacteroides ovatus Has the Potential to Be a Next-Generation Probiotic Strain
Yihan Shen1,2, Lingtong Meng1,2, Yanan Li3,4
1State Key Laboratory of Microbial Technology, Nanjing Normal University, 2 Xuelin Road, Qixia District, Nanjing, Jiangsu, China.
None:
Bacteroides ovatus (B. ovatus), a key member of the gut microbiota, is strongly associated with host health, thereby emerging as a promising candidate for the development of next-generation probiotics. This bacterium is linked to various pathophysiological conditions and shows potential probiotic biological activity, particularly in modulating metabolism and treating certain diseases. In the present review, we aim to provide a comprehensive synthesis of the established biological attributes of B. ovatus, while also elucidating the patterns and characteristics of its abundance fluctuations across diverse clinical indications. We also investigate the influence of probiotics, prebiotics, natural products, dietary patterns, and other extrinsic factors on the dynamic changes in B. ovatus abundance. Additionally, an evaluative and prospective analysis of the potential applications of B. ovatus in the realms of functional nutrition and specialized medical foods is presented. Finally, we highlight the transformative potential of B. ovatus in functional nutrition and specialized medical foods, providing a basis for the development of novel microbiome preparations.
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