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Robust T-Loss for medical image segmentation.

Alvaro Gonzalez-Jimenez1, Simone Lionetti2, Philippe Gottfrois1

  • 1Department of Biomedical Engineering, University of Basel, Hegenheimermattweg 167b, Allschwil, 4123, Switzerland.

Medical Image Analysis
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Summary

T-Loss, a new loss function for medical image segmentation, effectively handles noisy masks using a Student-t distribution. It outperforms traditional methods in skin lesion and lung segmentation tasks.

Keywords:
Deep learningLabel noiseLung segmentationMedical image segmentationRobust loss functionSkin lesion segmentationStudent-t distribution

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Area of Science:

  • Medical Imaging
  • Computer Vision
  • Machine Learning

Background:

  • Medical image segmentation is crucial for diagnosis and treatment planning.
  • Noisy labels in medical datasets are a common challenge, impacting model performance.
  • Existing loss functions struggle with significant label noise.

Purpose of the Study:

  • Introduce T-Loss, a novel loss function for robust medical image segmentation.
  • Address the challenge of noisy masks in medical imaging datasets.
  • Improve segmentation accuracy and resilience to annotation errors.

Main Methods:

  • Derived T-Loss from the negative log-likelihood of the Student-t distribution.
  • Utilized a single, dynamically optimized parameter to control sensitivity to noisy labels.
  • Conducted extensive experiments on public skin lesion and lung segmentation datasets.
  • Simulated various types of label noise to test robustness.

Main Results:

  • T-Loss significantly outperformed traditional loss functions in Dice scores on skin lesion and lung segmentation tasks.
  • Demonstrated remarkable resilience to simulated label noise, mimicking human annotation errors.
  • Showcased the adaptive nature of the T-Loss parameter in preventing noisy memorization during training.

Conclusions:

  • T-Loss offers a robust and effective solution for medical image segmentation with noisy labels.
  • Its adaptive parameter control makes it a promising alternative for real-world medical imaging applications.
  • The proposed method enhances segmentation accuracy and reliability in the presence of data imperfections.