Analysis of 5 cases of PICC removal difficulty caused by fibroblastic sleeve

Xiajuan Lyu1, Man Li2

  • 1Nursing department, Wuxi Xinwu District Xinrui Hospital (Wuxi branch of Ruijin Hospital Shanghai JiaoTong University School of Medicine), Jiangsu Province, 214028, Wuxi City, China.

Discover Oncology
|July 31, 2025
PubMed
Abstract

Insights

Difficult peripherally inserted central catheter (PICC) removal due to fibroblastic sleeve formation can be overcome. Thrombolysis with urokinase and tourniquet application successfully facilitated removal in five patients.

Area of Science:

  • Vascular Access Management
  • Interventional Radiology
  • Medical Device Complications

Background:

  • Fibroblastic sleeve formation around peripherally inserted central catheters (PICCs) can impede removal.
  • This complication necessitates investigation into effective removal strategies.
  • Understanding the mechanism of adhesion is crucial for patient care.

Purpose of the Study:

  • To investigate difficulties and solutions for PICC removal in patients with fibroblastic sleeve formation.
  • To evaluate a specific treatment approach for challenging PICC removals.
  • To identify factors aiding successful removal in cases of catheter adhesion.

Main Methods:

  • Case series of five patients experiencing difficulty removing PICCs due to fibroblastic sleeves.
  • Involved basilic, brachial, and cephalic veins.
  • Ultrasonography was used to rule out phlebitis and thrombosis prior to intervention.

Main Results:

  • A fibroblastic sleeve wrapping the catheter tip caused significant removal resistance.
  • Successful removal was achieved using urokinase thrombolysis and tourniquet application.
  • The combined approach addressed the adhesion and facilitated device extraction.

Conclusions:

  • Tourniquet application, 11-15 cm above the puncture site, may aid PICC removal.
  • This technique is beneficial for fibroblastic sleeve formation or catheter adhesion.
  • It offers a practical solution for difficult PICC removals.