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Published on: September 20, 2018
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[A case of brucella endocarditis in Tunisia]
Oussema Haddar1,2, Rania Ammar3,2, Mabrouk Bahloul3,2
1Service de cardiologie, Centre hospitalier universitaire Hédi Chaker de Sfax, Tunisie.
Medecine Tropicale Et Sante Internationale
|August 1, 2025
Summary
Brucella endocarditis, a rare complication of brucellosis, is difficult to diagnose. Early diagnosis and a multidisciplinary approach including surgery and antibiotics improve outcomes for this serious infection.
Area of Science:
- Infectious Diseases
- Cardiology
- Microbiology
Background:
- Brucella endocarditis (BE) is a rare but severe complication of brucellosis, often fatal.
- Diagnosis is challenging due to non-specific symptoms and low prevalence.
Observation:
- A 59-year-old man with a mechanical aortic prosthesis presented with heart failure, prosthetic disconnection, and aortic annulus abscess.
- Negative blood cultures initially complicated diagnosis, but serologic testing and surgical specimen culture confirmed Brucella melitensis infection.
Findings:
- The patient underwent prosthesis replacement, abscess drainage, and prolonged antibiotic therapy (doxycycline, cotrimoxazole, rifampicin).
- Despite postoperative complications, the patient achieved favorable hemodynamic and infectious outcomes.
Implications:
- This case underscores the necessity of a multidisciplinary approach for diagnosing BE.
- Early diagnosis via targeted serologic testing and cardiac imaging, coupled with surgical intervention and appropriate antibiotics, is crucial for improving patient prognosis.
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