A Rare Cutaneous Tumor With Unusual Dermoscopic Features

Area of Science:

• Dermatology
• Oncology
• Medical Imaging

Background:

• Biphasic adnexal tumors are rare skin neoplasms.
• Preoperative diagnosis can be challenging due to subtle clinical presentations.
• Accurate diagnosis is crucial for appropriate management and patient outcomes.

Purpose of the Study:

• To highlight subtle dermoscopic features suggestive of biphasic adnexal tumors.
• To emphasize the role of histopathology in definitive diagnosis.
• To explore the potential of AI in improving preoperative recognition of rare cutaneous tumors.

Main Methods:

• Review of dermoscopic images of biphasic adnexal tumors.
• Analysis of histopathological findings.
• Discussion of potential applications of AI in dermatological diagnostics.

Main Results:

• Specific dermoscopic clues including milia-like cysts, white structureless areas, and peripheral vessels were identified.
• Histopathology confirmed the diagnosis in all cases.
• AI-driven tools show promise for enhancing preoperative recognition of rare tumors like cutaneous sarcomas (CS).

Conclusions:

• Dermoscopy provides valuable clues for suspecting biphasic adnexal tumors.
• Histopathology remains the gold standard for diagnosis.
• AI integration could significantly improve the preoperative diagnosis of rare cutaneous neoplasms, including CS.