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Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
94
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
96
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
57
Renal Drug Clearance: Overview01:06

Renal Drug Clearance: Overview

338
Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...
338
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

73
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Related Experiment Video

Updated: Sep 13, 2025

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
05:34

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

Published on: July 18, 2025

150

Renal Long COVID: A Scoping Review.

Marcella M Frediani1, Heitor S Ribeiro1, Geraldo F Busatto2

  • 1Laboratório de Investigação 12, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Kidney Medicine
|August 1, 2025
PubMed
Summary
This summary is machine-generated.

Long COVID can lead to kidney problems like chronic kidney disease (CKD) development and progression. Acute kidney injury (AKI) during COVID-19 infection may increase the risk of renal long COVID, necessitating kidney function monitoring post-recovery.

Keywords:
Chronic kidney diseaseend-stage kidney diseasekidney replacement therapynephrologypost-acute COVID-19 syndrome

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Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
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Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • The long-term effects of coronavirus disease 2019 (COVID-19) on kidney health, termed renal long COVID, are not fully understood.
  • Evidence suggests a potential link between COVID-19 infection and subsequent kidney complications.

Purpose of the Study:

  • To conduct a scoping review describing the existing evidence on renal long COVID.
  • To synthesize findings on kidney-related outcomes in adult COVID-19 survivors experiencing long COVID.

Main Methods:

  • A comprehensive scoping review following Joanna Briggs Institute and PRISMA-ScR guidelines.
  • Searched MEDLINE, Embase, and other databases from inception to February 2025 for studies on kidney outcomes in adult COVID-19 survivors with long COVID data.

Main Results:

  • 37 studies (38 reports) including over 1.3 million individuals were analyzed.
  • Chronic kidney disease (CKD) development ranged from 0.4%-45%, and progression from 8%-49%.
  • Studies reporting higher frequencies of acute kidney injury (AKI) showed increased rates of renal long COVID.

Conclusions:

  • Renal long COVID, including CKD development and progression, is a potential post-COVID-19 complication.
  • Acute kidney injury (AKI) during acute COVID-19 may be associated with increased risk of renal long COVID.
  • Long-term kidney function monitoring after COVID-19 is recommended for early diagnosis and intervention.