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Published on: December 13, 2018
[Corrigendum] IL‑21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR‑125a‑3p axis in
Lei Yan1, Jing Zhang2, Dong Guo1
1Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.
Abstract:
Following the publication of the above article, an interested reader drew to the authors' attention that their paper was found to contain data with a previous article that had been published in the journal Oncotarget (Figs. 2C and 4B), and in a paper that appeared subsequently in the journal Molecular Cancer. All cases involved the sharing of Transwell assay data, and the other papers in question were published by the same authors/the same research group. After having examined their original data, the authors realized that Figs. 2 and 4 had been inadvertently assembled incorrectly in the above paper. Specifically, Figs. 2C and D, and 4B and D, showing the results of Transwell assay experiments indicating the effects of IL‑21R knockdown or co‑transfection with IL‑21R and miR‑125a mimic on cell invasion in HGC‑27 and MKN‑45 cell lines, contained erroneous images. The revised versions of Figs. 2 and 4, featuring replacement data for Figs. 2C and D and 4B and D, showing the correct data obtained for the effects of IL‑21R knockdown or co‑transfection with IL‑21R and miR‑125a mimic on cell invasion, are shown on the next page. All authors confirm that the errors made in Figs. 2C and D and 4B and D did not influence the final conclusions reported in the above article, and they thank the Editor of International Journal of Oncology for granting them the opportunity to publish a Corrigendum. All the authors agree to the publication of this Corrigendum, and apologize for the inconvenience to the readers. [International Journal of Oncology 54: 7‑16, 2019; DOI: 10.3892/ijo.2018.4612].
Insights
This corrigendum corrects errors in figures showing Transwell assay data for IL-21R knockdown and miR-125a mimic effects on cell invasion. The authors confirm the original conclusions remain unaffected by these data presentation errors.
Area of Science:
- Oncology
- Molecular Biology
- Cell Biology
Context:
- A previous publication in International Journal of Oncology contained errors in data presentation.
- The errors involved incorrect image assembly in Transwell assay data figures (Figs. 2C, 2D, 4B, 4D).
- These figures depicted the effects of IL-21R knockdown or co-transfection with IL-21R and miR-125a mimic on cell invasion in HGC-27 and MKN-45 cell lines.
Purpose:
- To issue a correction (Corrigendum) for inadvertently incorrect figures in a published article.
- To present the revised figures with accurate data for Transwell assay experiments.
- To clarify that the errors did not alter the study's final conclusions.
Summary:
- This corrigendum addresses the inadvertent incorrect assembly of images in Figures 2 and 4 of a previously published article.
- Specifically, Figures 2C, 2D, 4B, and 4D contained erroneous Transwell assay data concerning IL-21R knockdown and miR-125a mimic effects on cell invasion.
- Revised figures with corrected data are provided, and the authors confirm that the core conclusions of the original study remain valid.
Impact:
- Ensures data integrity and accuracy in scientific literature.
- Provides corrected information for researchers studying IL-21R, miR-125a, and cell invasion.
- Maintains transparency and trust within the scientific community by promptly addressing data presentation errors.
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