Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

One-Compartment Model: IV Infusion01:09

One-Compartment Model: IV Infusion

286
Intravenous (IV) infusion is often utilized when continuous and controlled drug delivery is necessary, such as during surgery or in the treatment of chronic diseases. This method offers numerous advantages, including immediate drug action, precise control over dosage, and bypassing the first-pass metabolism.
The one-compartment model for IV infusion uses mathematical equations to describe the rate of change in drug quantity in the body. At steady-state or infusion equilibrium, the drug input...
286
Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

301
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
301
Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

146
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
146
Two-Compartment Open Model: IV Infusion01:15

Two-Compartment Open Model: IV Infusion

336
A two-compartment model is a vital tool in pharmacokinetics, providing an essential understanding of drug behavior, especially for those administered via zero-order intravenous infusion. This model outlines two compartments: the central compartment, where elimination occurs, and the peripheral compartment.
The model illustrates the decrease in plasma drug concentration from the central compartment with a specific equation. It shows that under steady-state conditions, the drug's input rate...
336
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

137
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
137
Hemodialysis III: Nursing Management01:25

Hemodialysis III: Nursing Management

189
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
189

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An interpretable combinatorial data-mining framework for predicting new-onset hypertension in the general population.

Hypertension research : official journal of the Japanese Society of Hypertension·2026
Same author

Postmortem blood examination revealed prevalence of heart failure and its comorbidities in bathing-related deaths in older Japanese adults.

Journal of forensic and legal medicine·2026
Same author

Postoperative Results of Posterior Ankle Impingement Syndrome in Athletes and Its Clinical Features.

Orthopaedic journal of sports medicine·2026
Same author

Reconstruction of Partial Achilles Tendon Rupture After Corticosteroid Injection Using the Midsubstance SpeedBridge Technique With Platelet-Rich Plasma: A Case Report.

Cureus·2026
Same author

Economic consequences when enteral tube feeding intolerance causes unplanned discontinuation in hospitalized older patients with gastroesophageal reflux disease.

Clinical nutrition ESPEN·2026
Same author

L-GILZ is essential for cardiac function and protects against pressure overload-induced hypertrophy and dysfunction in mice.

Asian heart journal·2025

Related Experiment Video

Updated: Sep 13, 2025

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
07:17

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis

Published on: August 17, 2022

2.7K

Calculation of Absolute Blood Volume Using Intermittent Infusion Hemodiafiltration.

Tomoyuki Tanaka1, Tomohiro Matsui1, Keigo Imagawa2

  • 1From the Department of Clinical Engineering, Faculty of Health Care Sciences, Jikei University of Health Care Sciences, Osaka, Japan.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|August 1, 2025
PubMed
Summary
This summary is machine-generated.

Calculating initial absolute blood volume in dialysis patients is simplified with intermittent hemodiafiltration and relative blood volume monitoring. This method offers an accessible approach for precise blood volume assessment during treatment.

Keywords:
absolute blood volumebioelectrical impedance analysisintermittent infusion hemodiafiltrationrelative blood volume

More Related Videos

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.1K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

19.6K

Related Experiment Videos

Last Updated: Sep 13, 2025

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis
07:17

Evaluation of Fluid Overload by Bioelectrical Impedance Vectorial Analysis

Published on: August 17, 2022

2.7K
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
09:09

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock

Published on: November 3, 2023

1.1K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

19.6K

Area of Science:

  • Nephrology
  • Physiology
  • Medical Technology

Background:

  • Accurate determination of absolute blood volume (ABV) is crucial for optimizing dialysis treatment.
  • Existing methods for ABV measurement can be complex or invasive.

Purpose of the Study:

  • To evaluate the efficacy of a combined continuous relative blood volume (RBV) measurement and dialysate infusion method for determining initial absolute blood volume in dialysis patients.
  • To assess the applicability of this method in the context of intermittent infusion hemodiafiltration (iHDF).

Main Methods:

  • The study applied a method combining RBV monitoring with intermittent dialysate infusions (dilutions) to measure initial and final absolute blood volumes.
  • Measurements were taken during five sequential intermittent dialysate infusions in patients undergoing iHDF.
  • Absolute blood volumes were calculated based on observed relative blood volume changes during each dilution.

Main Results:

  • Initial absolute blood volumes measured across the first to fifth dilutions ranged from 4,288 ± 900 ml to 3,871 ± 929 ml.
  • Specific initial volumes ranged from 79.5 ± 12.5 ml/kg to 72.7 ± 13.9 ml/kg.
  • A statistically significant decrease (p < 0.05) in initial absolute blood volume was observed from the first to the fifth dilution, indicating a potential cumulative effect or adjustment.

Conclusions:

  • The combined use of intermittent infusion hemodiafiltration and relative blood volume measurement provides an easy and effective method for determining absolute blood volume in dialysis patients.
  • This approach offers a practical tool for clinicians to assess and manage patient fluid status accurately.