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Related Concept Videos

Issues And Trends In Healthcare Delivery System01:29

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
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Drug Delivery: Overview01:16

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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
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Drug Delivery: Miscellaneous Routes01:22

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
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Therapeutic Index01:13

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The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
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Additional Routes of Drug Administration01:18

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Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
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November 2025 therapeutic delivery: industry update.

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May 2025 therapeutic delivery: industry update.

Elaine Harris1

  • 1School of Chemical and BioPharmaceutical Science, Technological University Dublin, Dublin 7, Ireland.

Therapeutic Delivery
|August 1, 2025
PubMed
Summary
This summary is machine-generated.

Two drug delivery technologies received approvals this month, including Halozyme

Keywords:
Emerging technologiesGlaucomaOral deliveryParenteral deliveryParkinson’s DiseasePersonalized deliveryProstate Cancer

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Area of Science:

  • Drug delivery technologies
  • Biotechnology advancements
  • Therapeutic innovations

Background:

  • Recent approvals highlight the success of Halozyme's Enhanze drug delivery technology with BMS's Opdivo and Johnson & Johnson's DARZALEX FASPRO®.
  • Collaborations between industry and charities are advancing research for rare diseases like Duchenne muscular dystrophy and Epidermolysis Bullosa.

Discussion:

  • Successful clinical trial data was presented for diverse therapeutic delivery systems.
  • Innovations include an intravitreal implant for glaucoma, precision cell therapy for Parkinson's disease, and a novel therapy for prostate cancer.

Key Insights:

  • The Enhanze technology demonstrates significant potential in pharmaceutical applications.
  • Diverse therapeutic delivery systems are showing promising clinical results across various medical fields.
  • Collaborative efforts are crucial for tackling complex diseases and advancing medical treatments.

Outlook:

  • Continued development and adoption of advanced drug delivery technologies are expected.
  • Further research and clinical trials will likely yield new treatment options for numerous conditions.
  • Industry-charity partnerships will play a vital role in accelerating rare disease research and therapeutic development.