An unusual chest lesion with dual pathologies

Area of Science:

• Dermatology
• Pathology

Background:

• Granuloma faciale (GF) is a rare, chronic inflammatory skin condition.
• Typically presents on the face with characteristic papules and plaques.

Observation:

• A 66-year-old male with a history of GF and basal cell carcinomas (BCCs) presented with a chest lesion.
• The lesion was a pearly plaque, atypical for typical facial GF.

Findings:

• Biopsy confirmed extrafacial GF coexisting with a basal cell carcinoma (BCC).
• This represents a rare collision tumor, with GF occurring in an unusual location.

Implications:

• Extrafacial GF can mimic other skin conditions, complicating diagnosis.
• Highlights the necessity of histopathological examination for accurate diagnosis of atypical skin lesions.
• Underscores the potential for concurrent pathologies in patients with a history of skin cancer or inflammatory conditions.