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Aggrecan protects against plaque accumulation and is essential for proper microglial responses to plaques

Rocio A Barahona1, Nellie E Kwang1, Aashna R Kono-Soosaipillai1

  • 1Department of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, Irvine, CA 92697, USA.

Cell Reports
|August 1, 2025
PubMed

Keywords:
5xFADAlzheimer’s diseaseCP: Cell biologyCP: Neuroscienceaggrecanamyloid-betaextracellular matrixmicroglianeurodegenerationperineuronal netsplaques

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