Protocol for detecting oral squamous cell carcinoma in histopathology images using the momentum contrast framework
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Updated: Sep 13, 2025

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Published on: July 25, 2011
Xiaoyun Zhang1, Yue Fang2, Weibin Liao3
1School and Hospital of Stomatology, Peking University, Beijing 100081, China.
Abstract:
The detection of oral squamous cell carcinoma (OSCC) in histopathology images is crucial for improving diagnostic accuracy and patient outcomes. Here, we present a protocol for detecting OSCC in histopathology images using transfer learning. We describe steps for installing software and prerequisites, preparing datasets, and pretraining a model on images from various tissue types using the momentum contrast (MoCo) framework. We then detail procedures for evaluating the fine-tuned HistoMOCO model's performance on a test dataset.
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