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Updated: Aug 8, 2026

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The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury
Published on: October 21, 2017
[Morphometric research on the structural changes in the liver of mice undergoing multiple exposures to a stress
Biulleten' Eksperimental'Noi Biologii I Meditsiny
|December 1, 1985
Abstract:
C57BL/6 male mice were every day exposed to stressing influence. The liver was examined on day 4, 10, 21 after the start of the experiment and 3 days after the exposure was discontinued. These periods were characterized by increased concentration of ultrastructure membranes and intensified autophagocytosis. The volume changes in glycogen and autophagic vacuoles have been characterized by a strong correlation ratio. These changes were most prominent on day 10 of observation. The adaptive nature of changes is suggested.

