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Knowledge, concerns and experiences regarding family planning and pregnancy in NMOSD: A cross-sectional study from

Edgar Carnero Contentti1, Ricardo Alonso2, Verónica Tkachuk3

  • 1Neuroimmunology Unit, Department of Neurosciences, Hospital Aleman, Buenos Aires, Argentina; Center for Neuroimmunological Diseases in Rosario (CENRos), Neuroimmunology Clinic, Instituto de Neurología Cognitiva (INECO) Neurociencias Oroño, Rosario, Argentina.

Multiple Sclerosis and Related Disorders
|August 1, 2025
PubMed

We aimed to examine family planning (FP) experience and knowledge in NMOSD patients. We conducted a cross-sectional study using a web-based survey, addressing FP, pregnancy experiences before and after NMOSD diagnosis, unplanned pregnancies, neurologist advice, and perception of pregnancy. Of 105 participants, 55.2 % never discussing pregnancy with their neurologist, 30.8 % expressed a desire for pregnancy post-diagnosis, but only 7.6 % adjusted treatment. Unplanned pregnancies were common, and 11.4 % were advised against pregnancy. Relapses remained considerable (33.3 %), and miscarriages occurred in pre- and post-diagnosis pregnancies. FP remains insufficiently addressed in clinical settings, but it is essential to optimizing maternal and fetal outcomes.

Keywords:
Family planningLatin AmericaNeuromyelitis optica spectrum disorderPregnancy

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