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Related Experiment Videos

Estimation of plasma volume changes during marathon running.

R J Maughan, P H Whiting, R J Davidson

    British Journal of Sports Medicine
    |September 1, 1985
    PubMed
    Summary

    Marathon runners experienced significant fluid loss, with plasma volume decreasing by 6.5%. This fluid loss was evenly distributed between intracellular and extracellular compartments, impacting total body water during endurance running.

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    Area of Science:

    • Exercise Physiology
    • Sports Medicine
    • Human Physiology

    Background:

    • Marathon running involves substantial physiological stress and fluid loss.
    • Understanding fluid shifts is crucial for athlete performance and health.
    • Previous research indicates significant dehydration during prolonged endurance events.

    Purpose of the Study:

    • To quantify fluid loss and plasma volume changes in male marathon runners.
    • To investigate the relationship between hematological parameters and fluid shifts.
    • To determine the distribution of water loss between body compartments during a marathon.

    Main Methods:

    • 47 male runners' body weight, hemoglobin concentration, packed cell volume, serum albumin, and total protein were measured before and after a marathon.
    • Fluid loss was assessed by changes in body weight and calculated using hematological parameters.
    • Plasma volume (PV) changes were estimated from hematological data.

    Main Results:

    • Mean body weight decreased by 3.0%, with a 6.5% decrease in plasma volume (PV).
    • Serum total protein and albumin concentrations increased significantly, correlating with PV decrease.
    • Water loss was evenly distributed between intracellular and extracellular compartments, with total body water decreasing by approximately 5%.

    Conclusions:

    • Marathon running leads to significant plasma volume reduction and fluid shifts.
    • Hematological markers effectively indicate fluid loss during endurance exercise.
    • Water loss during marathons affects both intracellular and extracellular fluid compartments.

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