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Transparent brain tumor detection using DenseNet169 and LIME.

Lincy Annet Abraham1, Gopinath Palanisamy2, Goutham Veerapu1

  • 1School of Electronics Engineering, Vellore Institute of Technology, Vellore, 632014, Tamilnadu, India.

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|August 1, 2025
PubMed
Summary

A novel deep learning model, DenseNet169-LIME-TumorNet, accurately classifies brain tumors using MRI scans. This interpretable AI enhances diagnostic reliability and supports clinical decision-making with high accuracy.

Keywords:
Brain tumor detectionDeep learningDenseNet169Local Interpretable Model-agnostic Explanations (LIME)Medical imagingTransfer learning

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence in Medicine
  • Deep Learning for Medical Diagnosis

Background:

  • Brain tumor classification is vital for diagnosis and treatment planning.
  • Existing deep learning models require improvement in performance and interpretability.
  • Medical imaging analysis demands accurate and reliable automated tools.

Purpose of the Study:

  • To propose DenseNet169-LIME-TumorNet, a deep learning model for enhanced brain tumor classification.
  • To improve classification performance and model interpretability using DenseNet169 and LIME.
  • To evaluate the model's efficiency and practical utility in clinical settings.

Main Methods:

  • Development of DenseNet169-LIME-TumorNet, integrating DenseNet169 with LIME (Local Interpretable Model-agnostic Explanations).
  • Training and evaluation on the Brain Tumor MRI Dataset (2,870 images, three tumor types).
  • Comparative analysis against established deep learning architectures (Inception V3, ResNet50, etc.).

Main Results:

  • Achieved a classification accuracy of 98.78% on brain tumor classification.
  • Outperformed several widely used deep learning architectures in accuracy.
  • Demonstrated minimal computational overhead for efficient deployment.

Conclusions:

  • DenseNet169-LIME-TumorNet offers superior performance and interpretability for brain tumor classification.
  • The model's efficiency and transparency support clinical decision-making and real-time diagnostics.
  • Future work should focus on multi-modal learning and real-time AI-assisted diagnostic applications.