Recanalization times in patients with deep vein thrombosis with and without thrombophilia

ObjectiveHypercoagulability, called thrombophilia, has a vital role in the development of deep vein thrombosis. During the healing process of patients with thrombosis, the recanalization process in deep veins takes longer in some patients. This study was designed to investigate the role of thrombophilia in this critical process, considering that thrombophilia may be one of the reasons for the prolonged recanalization period.MethodThe study was retrospectively analyzed in 118 patients with deep vein thrombosis. Patients were grouped according to thrombophilia or not. Patients were divided into early and late recanalization groups according to the recanalization status on ultrasonography at the sixth month. The thrombophilia status of these groups was evaluated.Results62 of the patients were female, and 56 were male. The mean age was 41.92 ± 10.26 years. Thrombophilia was more common in women. There was a significant difference between the mean age and thrombophilia status; the mean age was lower in the thrombophilia group (p = .029). No statistically significant difference was found between age and recanalization times (p = 0, 274). Recurrence rates were also higher in the F5 Leiden and Protein-S deficiency group.ConclusionThe presence of thrombophilia affects patients' recanalization time and, therefore, suggests the need to reevaluate treatment strategies.