Activation of spinal cord interneurons which process inputs from the femoral-saphenous vein

Recordings were made from single spinal cord interneurons which could be activated by electrical stimulation of afferents terminating in the wall of the femoral-saphenous vein. Interneurons were either excited or both excited and inhibited by venous afferent stimulation. Most of the venous afferent-driven interneurons could also be driven by electrical activation of A-alpha beta muscle and cutaneous afferents. Stimulation of several different muscle nerves drove single interneurons.