Related Experiment Video
Updated: Sep 13, 2025

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Comparing illness perceptions in inflammatory bowel disease and irritable bowel syndrome
Kate MacKrill1, Christopher Bass2, Keith Petrie3
1Department of Psychological Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland 1142, New Zealand; Department of Psychological Medicine, Division of Medicine, Middlemore Hospital, Auckland 2025, New Zealand.
Patients with Irritable Bowel Syndrome (IBS) perceive their condition more negatively than those with Inflammatory Bowel Disease (IBD). These negative illness perceptions in IBS patients significantly impact symptom reporting and anxiety levels.
Area of Science:
- Gastroenterology
- Psychology
- Health Psychology
Background:
- Illness perceptions may differ between functional and organic gastrointestinal conditions.
- Functional conditions, like Irritable Bowel Syndrome (IBS), lack objective causes for symptoms, potentially leading to more adverse illness perceptions compared to organic conditions like Inflammatory Bowel Disease (IBD).
Purpose of the Study:
- To compare illness perceptions between patients diagnosed with IBS and IBD.
- To investigate the impact of these illness perceptions on symptom reporting and symptom-specific anxiety in both patient groups.
Main Methods:
- A cross-sectional study involving 70 IBS patients and 198 IBD patients.
- Utilized the Brief Illness Perceptions Questionnaire to assess patient perceptions.
- Employed independent samples t-tests and regression analyses to compare groups and examine outcome effects.
Main Results:
- IBS patients reported significantly lower perceptions of personal control, treatment control, timeline, and coherence compared to IBD patients.
- IBS patients perceived greater consequences and identity related to their condition.
- Illness identity and emotional response significantly predicted symptom reporting and anxiety, with a stronger effect observed in IBS patients.
Conclusions:
- Patients with IBS exhibit more adverse illness perceptions than those with IBD.
- These perceptions more strongly correlate with symptom reporting and anxiety in IBS patients.
- Healthcare providers should consider the psychological impact of a functional diagnosis on patient perceptions and functioning.
Related Concept Videos
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

