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Updated: Sep 13, 2025
Low-intensity Blast Wave Model for Preclinical Assessment of Closed-head Mild Traumatic Brain Injury in Rodents
Published on: November 6, 2020
The complex dynamics of maxillofacial trauma in blast and fragmentation injuries: Current understanding and gaps in
Ricardo Grillo1, Leandro Bottura1, Bernardo Correia Lima2
1Department of Oral and Maxillofacial Surgery, University of São Paulo, São Paulo, SP, Brazil.
Abstract:
Recent epidemiological data demonstrate a significant rise in blast-induced maxillofacial trauma incidences in both military and civilian settings. This study aimed to comprehensively analyze maxillofacial trauma caused by heavy weaponry, examining blast dynamics, ballistic forces, and fragmentation effects. A comprehensive literature review was conducted using PubMed, SciSpace, and Google Scholar, incorporating studies on blast injuries, ballistic trauma, and war-related maxillofacial damage. Keywords included "maxillofacial injuries", "blast injuries", "ballistic trauma", "high-energy trauma", "heavy weapon injuries", "shock waves", "fragmentation injuries", "missile wounds", "grenade injuries", "shrapnel injuries", and "war-related maxillofacial trauma". Inclusion criteria covered case reports, retrospective analyses, reviews, and clinical trials, while non-human and irrelevant studies were excluded. Data extraction and synthesis were performed to categorize injury mechanisms and surgical challenges. The findings revealed distinct injury patterns, including comminuted fractures, barotrauma-induced sinus ruptures, and thermal-chemical burns. Blast waves preferentially damaged thin bony structures, while high-velocity shrapnel caused widespread soft-tissue disruption. Surgical management is complicated by contamination, delayed necrosis, and polytrauma, necessitating multidisciplinary approaches. Emerging solutions, such as 3D-printed implants and damage-control surgery, show promise but require further validation. Heavy weaponry induces complex maxillofacial trauma that demands tailored, multidisciplinary care. Our review highlights critical gaps in existing protocols and underscores the need for advanced biomaterials, staged reconstruction, and battlefield-adapted surgical strategies. Future research should focus on predictive modeling and standardized guidelines to optimize outcomes in blast-related injuries.
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