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ESR Essentials: common performance metrics in AI-practice recommendations by the European Society of Medical Imaging
Michail E Klontzas1,2, Kevin B W Groot Lipman3, Tugba Akinci D' Antonoli4
1Artificial Intelligence and Translational Imaging (ATI) Lab, Department of Radiology, School of Medicine, University of Crete, Heraklion, Greece.
European Radiology
|August 3, 2025
Summary
Radiologists need practical guidance on evaluating artificial intelligence (AI) performance in radiology. This involves selecting appropriate metrics and performing local validation to ensure AI tools are safe and effective for clinical use.
Area of Science:
- Medical Imaging
- Artificial Intelligence in Healthcare
- Radiology Informatics
Background:
- Artificial intelligence (AI) is increasingly integrated into radiology workflows.
- Evaluating the performance of AI tools is crucial for ensuring patient safety and clinical utility.
- Radiologists require standardized methods for assessing AI performance.
Purpose of the Study:
- To provide radiologists with practical recommendations for evaluating AI performance in radiology.
- To outline key performance metrics for AI in medical imaging.
- To address common pitfalls and offer mitigation strategies for AI evaluation.
Main Methods:
- Review of key performance metrics including segmentation overlap, test-based metrics (sensitivity, specificity, AUC-ROC), and outcome-based metrics (precision, NPV, F1-score, MCC, AUC-PR).
- Emphasis on local validation using independent datasets and consideration of deployment context.
- Discussion of common pitfalls like metric overreliance, misinterpretation in low-prevalence settings, and workflow integration challenges.
Main Results:
- Key recommendations include task-specific metric selection, local validation, and considering the clinical context.
- Strategies are provided to mitigate pitfalls such as threshold selection and prevalence-adjusted evaluation.
- Guidance on assessing AI-generated image quality is also included.
Conclusions:
- Radiologists must critically evaluate AI performance metrics, recognizing their limitations and the need for clinical utility assessment.
- Independent, context-specific evaluation is essential for safe and effective AI deployment in radiology.
- Aligning performance metrics with the AI's intended task (segmentation, detection, classification) and target population is vital for improving diagnostic accuracy and patient outcomes.

