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Dynamics of root caries in older adults using high-fluoride toothpaste
Soraya León1, Natalia Gómez1, Karla Gambetta-Tessini2
1Gerodontology and Cariology Unit, Oral Rehabilitation Department, Faculty of Dentistry, University of Talca, Talca, Chile, 1 Poniente 1141, Talca, Chile.
Journal of Dentistry
|August 3, 2025
Summary
High-fluoride toothpaste (5000 ppm F) effectively inactivates root caries lesions (RCLs) in older adults, maintaining inactivity over two years. This contrasts with 1450 ppm F, which shows more variable lesion activity and reactivation.
Area of Science:
- Dental research
- Geriatric dentistry
- Caries management
Background:
- Root caries lesions (RCLs) pose a significant challenge in older adults.
- Assessing the efficacy of different fluoride concentrations in dentifrices is crucial for managing RCLs.
Purpose of the Study:
- To compare the activity patterns of root caries lesions (RCLs) treated with 1450 ppm F and 5000 ppm F dentifrices.
- To evaluate the long-term stability of lesion inactivation in community-dwelling older adults.
Main Methods:
- Utilized data from a randomized controlled clinical trial involving 2071 RCLs over two years.
- Applied Modified Nyvad's criteria to categorize lesion activity at baseline, one year, and two years.
- Employed bivariate analyses, Cochrane Q test, and mixed logistic regression to analyze activity patterns.
Main Results:
- 5000 ppm F toothpaste led to consistent inactivation: 64% of active lesions became inactive and stayed inactive (A-I-I), and 30% remained inactive (I-I-I).
- 1450 ppm F showed variable patterns: only 17.8% followed A-I-I, 20.4% remained I-I-I, with others fluctuating between activity and inactivity.
- Higher fluoride concentration (5000 ppm F) significantly reduced lesion reactivation compared to 1450 ppm F.
Conclusions:
- 5000 ppm F toothpaste promotes stable and consistent inactivation of RCLs in older adults.
- Higher fluoride concentrations offer more effective and predictable long-term management of root caries.
- The findings support the use of high-fluoride dentifrices for enhanced control of root caries in geriatric populations.
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