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Folate and nutrition.

J Zittoun

    Chemioterapia : International Journal of the Mediterranean Society of Chemotherapy
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Nutritional folate deficiency can cause various health issues, impacting the nervous and immune systems, pregnancy, and newborns. Prophylaxis with folic acid is recommended for high-risk groups.

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    Area of Science:

    • Nutrition and Dietetics
    • Biochemistry
    • Clinical Medicine

    Background:

    • Nutritional folate deficiency is a widespread issue with significant health implications.
    • While hematological effects are well-documented, other consequences remain less understood.
    • Identifying at-risk populations is crucial for effective intervention.

    Purpose of the Study:

    • To review the causes and diverse consequences of nutritional folate deficiency.
    • To highlight physiological and pathological conditions associated with folate deficiency.
    • To discuss the benefits of folic acid prophylaxis in vulnerable populations.

    Main Methods:

    • Literature review of causes and effects of folate deficiency.
    • Identification of at-risk groups including pregnant women, infants, elderly, alcoholics, and ICU patients.

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  • Analysis of the role of folic acid supplementation.

    • Main Results:

    • Folate deficiency impacts hematological, immune, nervous, and reproductive systems.
    • Pregnancy, prematurity, elderly status, alcoholism, and critical illness increase deficiency risk.
    • Folic acid prophylaxis demonstrates benefits in high-risk individuals.

    Conclusions:

    • Folate deficiency has multifaceted health consequences beyond hematological effects.
    • Specific populations face elevated risks, necessitating targeted preventive strategies.
    • Folic acid supplementation is a key intervention for preventing and managing folate deficiency in at-risk groups.