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Artificial intelligence in orthopedics: fundamentals, current applications, and future perspectives
Jian Song1, Guang-Chao Wang1, Si-Cheng Wang2
1Department of Orthopedics, Trauma Orthopedics Center, Institute of Musculoskeletal Injury and Translational Medicine of Organoids, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Military Medical Research
|August 3, 2025
Summary
Artificial intelligence (AI) offers data-driven solutions to enhance orthopedic diagnostics and therapeutics, addressing limitations of traditional methods. This review explores AI
Area of Science:
- Orthopedic Surgery
- Medical Imaging
- Artificial Intelligence
Background:
- Traditional orthopedic diagnostics and treatments are often time-consuming and prone to errors.
- There is a growing need for efficient tools to improve orthopedic care.
- Artificial intelligence (AI) is increasingly being integrated into orthopedic practice.
Purpose of the Study:
- To provide a comprehensive overview of AI principles and their clinical applications in orthopedics.
- To examine machine learning and deep learning frameworks relevant to orthopedic research and practice.
- To highlight current AI applications and future directions in the field.
Main Methods:
- Review of AI core concepts and historical evolution.
- Examination of machine learning and deep learning frameworks for orthopedics.
- Exploration of AI applications in orthopedic image analysis, diagnosis, and treatment.
Main Results:
- AI applications span image analysis, disease diagnosis, surgical assistance, drug development, rehabilitation, and personalized therapy.
- AI tools aim to deepen clinician and researcher understanding of orthopedic conditions.
- Key challenges include data quality, model generalizability, and clinical validation.
Conclusions:
- AI presents significant potential to improve efficiency and accuracy in orthopedic care.
- Addressing challenges in data and validation is crucial for effective AI integration.
- Future directions focus on advancing AI technologies for safe and effective clinical use in orthopedics.

