Evidence-Based Substance Use Prevention With Adolescents in Sub-Saharan Africa: Challenges and Opportunities

Area of Science:

• Public Health
• Substance Use Prevention
• Global Health

Background:

• Youth substance use remains a significant public health concern in sub-Saharan Africa.
• Prevention science in the region is diverse, with varying levels of progress and challenges.
• Existing evidence-based programs like Keepin' it REAL and Unplugged show promise but require cultural adaptation.

Purpose of the Study:

• To review youth substance use prevention efforts in sub-Saharan Africa (2014-2024).
• To identify progress, challenges, and needs in prevention science.
• To propose a strategy for strengthening local capacity and implementing culturally adapted interventions.

Main Methods:

• Review of current evidence-based prevention programs and initiatives.
• Analysis of implementation, cultural adaptation, and effectiveness of interventions.
• Introduction of the Global Center for Applied Health Research's African Initiative model.

Main Results:

• Sub-Saharan Africa's diversity impacts prevention science across countries.
• There is a critical need for increased access to evidence-based interventions.
• Strengthening local capacity for leading prevention efforts is essential.

Conclusions:

• A multilevel approach considering structural determinants is crucial for effective prevention.
• Culturally adapted, evidence-based interventions are needed to address complex local landscapes.
• Increased funding and involvement of local researchers and youth are vital for policy change and program success.