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Carcinomas of the maxillary sinus: a retrospective study
Clinical Otolaryngology and Allied Sciences
|October 1, 1985
Summary
Radical surgery for maxillary sinus cancer, including maxillectomy and orbital exenteration, is necessary for clear margins. This approach, combined with radiotherapy, improves survival rates for patients with advanced disease.
Area of Science:
- Oncology
- Surgical Oncology
- Head and Neck Cancer
Background:
- Maxillary sinus carcinoma presents significant treatment challenges.
- Massive surgical procedures like maxillectomy and orbital exenteration are sometimes indicated.
- Evaluating the necessity and outcomes of such extensive surgeries is crucial.
Purpose of the Study:
- To assess the indications for and outcomes of massive surgery in maxillary sinus cancer.
- To determine the survival rates associated with maxillectomy and orbital exenteration.
- To identify factors influencing survival in these patients.
Main Methods:
- Retrospective review of 96 patients with maxillary sinus carcinoma.
- Analysis of treatment strategies, including surgery and radiotherapy.
- Evaluation of 5-year survival rates and prognostic factors.
Main Results:
- The absolute 5-year survival rate was 51% for patients treated with curative intent and with at least 5-year follow-up.
- Survival was significantly reduced in cases with close/positive margins, invasion of the anterior cranial fossa, cheek soft tissues, or positive cervical lymph nodes.
- Achieving clear surgical margins was associated with better outcomes.
Conclusions:
- Massive surgery (maxillectomy and orbital exenteration) is often necessary for curative treatment of maxillary sinus carcinoma to achieve clear margins.
- Combined modality treatment, including surgery and radiotherapy, is recommended for optimal survival.
- Patient factors like tumor invasion and lymph node status significantly impact prognosis.