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Related Experiment Video

Updated: Sep 13, 2025

Inducement and Evaluation of a Murine Model of Experimental Myopia
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Using large language models to generate child-friendly education materials on myopia.

Xuewei Li1,2,3,4, Yixuan Zhang1,3,4, Tonglei Zheng1,2,3,4

  • 1Department of Ophthalmology, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing, China.

Digital Health
|August 4, 2025
PubMed
Summary

Large language models (LLMs) can generate effective patient education materials for myopia. ChatGPT 4o performed best, showing high correctness and conciseness for both adult and child audiences.

Keywords:
ChatGPTMyopiaartificial intelligencelarge language modelspatient educationreadability

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Area of Science:

  • Ophthalmology
  • Artificial Intelligence
  • Medical Education

Background:

  • Myopia management requires clear, accessible patient education for children and parents.
  • Large language models (LLMs) offer a potential tool for generating such educational content.

Purpose of the Study:

  • To evaluate the efficacy of LLMs in creating patient education materials for childhood myopia.
  • To compare the performance of different LLMs and prompts in generating accurate and age-appropriate myopia information.

Main Methods:

  • Thirty-five common myopia questions were used with two prompts (adult- and child-directed).
  • Five ophthalmologists rated LLM responses on correctness, completeness, conciseness, and potential harm.
  • Readability was assessed using Flesch-Kincaid scores.

Main Results:

  • ChatGPT 4o received the highest ratings for correctness and conciseness across both prompts.
  • ChatGPT 4o demonstrated superior completeness for child-directed responses.
  • Child-directed prompts resulted in significantly more readable content for all evaluated LLMs.

Conclusions:

  • LLMs, especially ChatGPT 4o, show promise for creating myopia patient education materials for diverse age groups.
  • While effective, LLMs require further development for complex medical information and clinical application.