Related Experiment Videos
Plexiform schwannoma
Abstract:
A 33-year-old man had a multinodular tumor on his left index finger. Microscopy revealed a plexiform nerve sheath tumor resembling schwannoma. Including this case, 11 patients from 9 to 39 years old, have been reported with plexiform schwannoma. One patient had von Recklinghausen's neurofibromatosis, and all but one were free of recurrence from 1.5 to 6 years later. Plexiform schwannoma should be distinguished from plexiform neurofibroma because it appears to have neither a significant association with neurofibromatosis nor a propensity for malignant transformation.
Insights
Plexiform schwannoma is a rare tumor typically found on fingers. This condition rarely recurs and is not associated with neurofibromatosis or malignant transformation.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Plexiform schwannoma is a rare peripheral nerve sheath tumor.
- Distinguishing it from plexiform neurofibroma is crucial for patient management.
Observation:
- A case of a multinodular plexiform schwannoma on the left index finger of a 33-year-old male is presented.
- A review of reported cases indicates 11 patients diagnosed with plexiform schwannoma, aged 9 to 39 years.
Findings:
- Microscopic examination revealed a plexiform nerve sheath tumor with schwannoma-like features.
- Only one patient had von Recklinghausen's neurofibromatosis.
- Recurrence-free survival ranged from 1.5 to 6 years in all but one patient.
Implications:
- Plexiform schwannoma has a low recurrence rate and a favorable prognosis.
- It lacks a significant association with neurofibromatosis (NF1).
- Unlike plexiform neurofibroma, plexiform schwannoma does not show a propensity for malignant transformation.