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Related Experiment Videos

Plexiform schwannoma.

G M Kleinman, F J Sanders, J M Gagliardi

    Clinical Neuropathology
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Plexiform schwannoma is a rare tumor typically found on fingers. This condition rarely recurs and is not associated with neurofibromatosis or malignant transformation.

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    Area of Science:

    • Dermatology
    • Oncology
    • Pathology

    Background:

    • Plexiform schwannoma is a rare peripheral nerve sheath tumor.
    • Distinguishing it from plexiform neurofibroma is crucial for patient management.

    Observation:

    • A case of a multinodular plexiform schwannoma on the left index finger of a 33-year-old male is presented.
    • A review of reported cases indicates 11 patients diagnosed with plexiform schwannoma, aged 9 to 39 years.

    Findings:

    • Microscopic examination revealed a plexiform nerve sheath tumor with schwannoma-like features.
    • Only one patient had von Recklinghausen's neurofibromatosis.
    • Recurrence-free survival ranged from 1.5 to 6 years in all but one patient.

    Implications:

    • Plexiform schwannoma has a low recurrence rate and a favorable prognosis.
    • It lacks a significant association with neurofibromatosis (NF1).
    • Unlike plexiform neurofibroma, plexiform schwannoma does not show a propensity for malignant transformation.