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One risk assessment for genetically modified plants.

Muffy Koch1, Jaylee DeMond1, Matthew G Pence1

  • 1Simplot Plant Sciences, J. R. Simplot Company, Boise, ID, United States.

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|August 4, 2025
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Summary
This summary is machine-generated.

Streamlining genetically modified (GM) plant regulation requires a global risk assessment approach. Harmonizing reviews reduces redundancy, benefiting developers and ensuring wider access to GM plant advantages.

Keywords:
GMORNA interferencecisgeneslow riskregulatory efficiencyvegetative crops

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Area of Science:

  • Agricultural biotechnology
  • Environmental science
  • Food safety regulation

Background:

  • Regulatory agencies possess over 30 years of experience in assessing genetically modified (GM) plant safety.
  • Current per-country risk assessments for GM plants are redundant, creating significant burdens for developers and government resources.
  • Repeated safety reviews for import or cultivation permits are unnecessary as they do not alter the established safety profile of approved GM products.

Purpose of the Study:

  • To propose a unified global risk assessment model for genetically modified (GM) plants to enhance regulatory efficiency.
  • To advocate for the sharing of risk assessment summaries among countries to avoid duplicative evaluations.
  • To identify steps for a streamlined regulatory process, including a global approval system for low-risk traits.

Main Methods:

  • Analysis of existing regulatory practices for genetically modified (GM) plant risk assessments.
  • Proposal of a global risk assessment framework based on international standards.
  • Discussion of strategies for harmonizing regulatory reviews and approvals.

Main Results:

  • A global risk assessment model can significantly reduce regulatory redundancy and burden.
  • Sharing assessment summaries facilitates efficient review processes while maintaining national oversight.
  • Harmonization accelerates approvals, potentially broadening access to GM plant benefits.

Conclusions:

  • Adopting a single, global risk assessment for GM plants is a feasible and beneficial strategy.
  • Streamlined regulatory processes, including global reviews for low-risk traits, are essential for innovation.
  • Harmonized risk assessments will enable broader and more equitable access to the advantages offered by genetically modified plants.