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Rheumatic Manifestations in Patients with Idiopathic Inflammatory Bowel Disease: A Single Tertiary Centre,
Athanasios Kavvadias1, Maria Karavasili2, Eleftherios Pelechas3
1Department of Gastroenterology.
Mediterranean Journal of Rheumatology
|August 4, 2025
Summary
Inflammatory bowel disease (IBD) patients frequently have silent musculoskeletal issues, particularly enthesitis. Musculoskeletal ultrasound reveals a high prevalence of enthesitis in IBD, often without clinical symptoms.
Area of Science:
- Rheumatology
- Gastroenterology
- Medical Imaging
Background:
- Inflammatory bowel disease (IBD) is frequently linked to extraintestinal manifestations.
- Joint involvement and enthesitis are common, mimicking spondyloarthropathy.
- Enthesitis in IBD patients can be clinically silent, lacking overt signs or a spondylarthritis diagnosis.
Purpose of the Study:
- To determine the frequency and location of musculoskeletal manifestations in IBD patients using musculoskeletal ultrasound.
- To assess the prevalence of synovitis and enthesitis in a cohort of IBD patients.
Main Methods:
- Prospective recruitment of 50 IBD patients evaluated by a rheumatologist.
- Comprehensive musculoskeletal ultrasound of knees, patellae, and limbs, assessing 12 entheses.
- Scoring of ultrasound abnormalities using the Madrid Ankylosing Spondylitis Enthesitis Index.
Main Results:
- Musculoskeletal ultrasound identified synovitis in 24% and enthesitis in 64% of IBD patients.
- High rates of enthesitis were observed in the Achilles tendon (40.6%) and Quadriceps tendon (6.3%), with combined involvement.
- Specific enthesitis locations included Quadriceps tendon, Achilles tendon, and Patella.
Conclusions:
- Musculoskeletal ultrasound confirms significant prevalence of musculoskeletal manifestations in IBD.
- Enthesitis is the most common musculoskeletal finding in IBD patients.
- Ultrasound is crucial for detecting subclinical enthesitis in inflammatory bowel disease.
Keywords:
enthesitisinflammatory bowel diseasemusculoskeletal ultrasoundrheumatological manifestationsMore Related Videos
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