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Lupus Enteritis: Presentation as an Apparent Surgical Emergency - A Case Report
Aarti A Zope1, Shashank M Akerkar1, Pooja G Binnani2
1Department of Rheumatology, IC4 Mumbai Arthritis Clinic, Bhandup, Mumbai, Maharashtra, India.
Mediterranean Journal of Rheumatology
|August 4, 2025
Summary
Systemic Lupus Erythematosus (SLE) can cause acute abdominal pain due to lupus enteritis. Early steroid treatment resolved symptoms, avoiding surgery and highlighting the need for high clinical suspicion in SLE patients.
Area of Science:
- Rheumatology
- Gastroenterology
- Surgical Emergencies
Background:
- Systemic Lupus Erythematosus (SLE) is a complex autoimmune condition with diverse organ manifestations.
- Gastrointestinal (GI) involvement is a recognized feature of SLE, with oral lesions being most common.
- Acute abdomen in SLE patients necessitates careful evaluation due to multiple potential underlying causes.
Observation:
- This case report details a patient with SLE presenting with acute abdomen.
- The presentation was attributed to lupus enteritis (LE) or intestinal pseudo-obstruction (IPO), mimicking a surgical emergency.
- Surgical intervention was initially considered due to the severity of the abdominal symptoms.
Findings:
- Prompt diagnosis of lupus enteritis and initiation of corticosteroid therapy led to symptom resolution.
- The patient's condition improved without the need for surgical exploration.
- This highlights the importance of considering lupus-related GI complications in SLE patients with acute abdominal pain.
Implications:
- Heightened clinical suspicion for LE/IPO is crucial in SLE patients presenting with acute abdominal pain.
- Differentiating lupus-related GI issues from surgical emergencies is critical for appropriate management.
- Timely medical management can prevent unnecessary surgical interventions and associated complications in SLE patients.
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