Jove
Visualize
Contact Us

Related Experiment Videos

Oesophageal function tests: are they of value?

K S Channer, J P Virjee

    Clinical Radiology
    |September 1, 1985
    PubMed
    Summary

    Water and capsule transit times effectively assess oesophageal function in systemic sclerosis and diabetic autonomic neuropathy. These methods are sensitive and comparable to barium swallow for detecting motility disorders.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Revascularization with percutaneous coronary intervention does not affect androgen status in males with chronic stable angina pectoris.

    Andrology·2016
    Same author

    The role of androgen receptor CAG repeat polymorphism and other factors which affect the clinical response to testosterone replacement in metabolic syndrome and type 2 diabetes: TIMES2 sub-study.

    European journal of endocrinology·2013
    Same author

    Dyslipidaemia is associated with testosterone, oestradiol and androgen receptor CAG repeat polymorphism in men with type 2 diabetes.

    Clinical endocrinology·2011
    Same author

    Testosterone acts as an efficacious vasodilator in isolated human pulmonary arteries and veins: evidence for a biphasic effect at physiological and supra-physiological concentrations.

    Journal of endocrinological investigation·2009
    Same author

    Chronic atrial fibrillation: a systematic review of medical heart rate control management.

    Postgraduate medical journal·2009
    Same author

    Androgen receptor CAG repeat polymorphism is associated with serum testosterone levels, obesity and serum leptin in men with type 2 diabetes.

    European journal of endocrinology·2008
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Gastroenterology
    • Nuclear Medicine
    • Radiology

    Background:

    • Oesophageal dysmotility is common in systemic sclerosis and diabetic autonomic neuropathy.
    • Accurate assessment of oesophageal function is crucial for managing these conditions.

    Purpose of the Study:

    • To compare the sensitivity of water bolus transit time, barium swallow, and barium capsule transit time in detecting oesophageal motility disorders.
    • To evaluate oesophageal function in patients with systemic sclerosis and diabetic autonomic neuropathy.

    Main Methods:

    • Oesophageal function was assessed using oesophageal scintigraphy (water bolus transit time), barium swallow, and barium capsule transit time.
    • Study groups included controls, patients with systemic sclerosis, patients with diabetic autonomic neuropathy, and diabetic controls.

    Main Results:

    • Water and capsule transit times were significantly prolonged in systemic sclerosis and diabetic autonomic neuropathy patients compared to controls.
    • Capsule transit time showed high sensitivity, detecting abnormalities in most patients across all groups, including diabetic controls.
    • Barium swallow and water transit time also identified significant abnormalities in patient groups.

    Conclusions:

    • Water and capsule transit times are sensitive and effective tests for oesophageal motility disorders.
    • Capsule transit time offers a potentially more sensitive, cost-effective, and lower-radiation alternative to oesophageal scintigraphy.

    Related Experiment Videos