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Gall-bladder and colonic opacification following parenteral ioxaglate
Clinical Radiology
|September 1, 1985
Summary
A study found that 60% of patients receiving ioxaglate experienced gallbladder opacification hours later. This finding is a normal occurrence and does not indicate any kidney function impairment.
Area of Science:
- Radiology
- Pharmacology
Background:
- Ioxaglate is a urographic contrast medium.
- Gallbladder opacification is an uncommon side effect of urographic agents.
Purpose of the Study:
- To investigate the incidence and implications of gallbladder opacification following ioxaglate administration.
Main Methods:
- 50 in-patients with normal blood urea levels received ioxaglate (Hexabrix 320).
- Patients were not asked to fast post-administration.
- Gallbladder opacification was assessed 12-25 hours later.
Main Results:
- 60% of patients exhibited gallbladder opacification.
- This phenomenon was not previously reported with other urographic media, including low-osmolality agents.
- No fasting was enforced post-ioxaglate administration.
Conclusions:
- Gallbladder opacification after ioxaglate is a normal occurrence.
- This finding does not suggest impaired renal function.
- Clinical significance of this observation requires further evaluation.