Related Experiment Video
Updated: Sep 12, 2025

Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
Abdominal Necrotizing Fasciitis Secondary to Perforated Colon Cancer.
Anirudra Devkota1, Anish Shrestha1, Mariah M Bilalaga1
1Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Necrotizing fasciitis (NF), a severe infection, can rarely be caused by perforated colon cancer (CC). Early detection and surgical treatment are crucial for managing NF and preventing fatal outcomes from underlying conditions like CC.
Area of Science:
- Medical Case Study
- Surgical Pathology
- Oncology
Background:
- Necrotizing fasciitis (NF) is a life-threatening soft tissue infection characterized by rapid tissue necrosis.
- Perforated colon cancer (CC) is an extremely rare etiology for NF development.
Observation:
- This report details a unique case of NF arising secondary to a perforated colon cancer.
- The patient presented with clinical signs and symptoms indicative of severe soft tissue infection.
Findings:
- The study highlights the critical importance of considering rare underlying causes, such as perforated colon cancer, in the differential diagnosis of NF.
- Prompt surgical debridement and management of the underlying malignancy are essential for patient survival.
Implications:
- This case underscores the necessity of thorough diagnostic evaluation to identify uncommon etiologies of NF.
- It emphasizes the role of colon cancer screening in preventing severe complications and mortality associated with advanced disease.
More Related Videos
Related Concept Videos
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:

