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Updated: Sep 12, 2025
09:17
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
Published on: March 5, 2019
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Chiral Inorganic Nanomaterials for Biological Features.
Meiru Lu1,2, Aihua Qu3, Xue Huang1,2
1Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Accounts of Chemical Research
|August 4, 2025
Summary
Chiral inorganic nanomaterials offer tunable properties for advanced nanobiomedicine. Their enantioselective interactions with biomolecules are key for applications in sensing, therapy, and diagnostics.
Area of Science:
- Nanomaterials Science
- Chirality in Materials
- Biomedical Engineering
Background:
- Inorganic nanomaterials possess diverse structures and functions.
- Chirality influences nanomaterial properties like size, shape, and optical activity.
- Biological systems exhibit inherent chirality and enantioselectivity.
Purpose of the Study:
- To review recent advances in chiral inorganic nanomaterials.
- To summarize design principles, fabrication strategies, and applications.
- To highlight the role of chirality in nanobiomedicine.
Main Methods:
- Fabrication of chiral noble metals, metal oxides, semiconductors, and hybrid nanomaterials.
- Analysis of chirality origins and influencing factors (chiral molecules, CPL, magnetic fields).
- Investigation of biomedical applications including biosensing, biocatalysis, and theranostics.
Main Results:
- Chiral inorganic nanomaterials show enantioselective interactions with biomolecules (amino acids, DNA, proteins).
- These materials exhibit responsive properties (redox, enzyme, light, magnetic effects).
- Applications span biosensing, biocatalysis, immune modulation, and disease theranostics.
Conclusions:
- Chiral inorganic nanomaterials are crucial for nanobiomedicine.
- Precise design and synthesis enable advanced functional properties.
- Future opportunities lie in developing sophisticated chirality-based platforms.
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