Related Experiment Video
Updated: Sep 12, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
Endoscopic Guided Dilations without Intralesional Corticosteroid Injections: Pediatric Crohn's Patients Case Series
Leo Fawaz1, Yousif Slim2, Peter N Freswick3
1Pediatric Gastroenterology Fellowship-Children's Hospital of Michigan, Detroit, MI 48201, USA.
Insights
Pediatric Crohn's disease (CD) patients may not need intralesional corticosteroid (ILC) injections during endoscopic balloon dilation (EBD). Further trials are needed to confirm the efficacy of EBD without ILCs in achieving deep remission.
Area of Science:
- Pediatric Gastroenterology
- Inflammatory Bowel Disease Research
- Endoscopic Therapeutics
Background:
- Pediatric Crohn's disease (CD) management has evolved towards achieving deep remission using biologics.
- Endoscopic balloon dilation (EBD) is a minimally invasive option for stricturing CD.
- Intralesional corticosteroid (ILC) injections are traditionally used with EBD, but their necessity in deep remission is unclear.
Abstract:
Background and Clinical Significance: The treatment for pediatric Crohn's disease (CD) has shifted over the years from steroids and immunomodulators to biologics with the goal of histological and clinical remission. Endoscopic balloon dilation (EBD) has been utilized for stricturing disease, even in the pediatric population. EBD has been shown to be effective and minimally invasive, though historically, has been performed on patients with persistent mucosal inflammation. As such, intralesional corticosteroid (ILC) injections have been traditionally utilized during EBD. However, intralesional corticosteroid efficacy among pediatrics patients in deep endoscopic remission is unknown. Case Presentation: We report four patients that demonstrated at least initial successful dilations without intralesional steroid injections. Conclusions: The use of ILC injections during routine EBDs in pediatric patients should be further explored in randomized control trials.
More Related Videos
07:30Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
05:17Author Spotlight: Scope of LE-ULBD as a Safe, Effective, and Minimally Invasive Approach to Treat Lumbar Spinal Stenosis
Published on: February 9, 2024
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...