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Parotid Epithelial-Myoepithelial Carcinoma, Lymph Node Metastasis After 9 Years: A Case Report
Maria Rita Bianco1, Cosimo Galletti2, Antonino Maniaci2
1Otolaryngology, Department of Health Science, University of Catanzaro, 88100 Catanzaro, Italy.
Reports (MDPI)
|August 4, 2025
Summary
Epithelial-myoepithelial carcinoma (EMC), a rare salivary gland tumor, can recur locally. This case highlights a rare 9-year loco-regional lymph node metastasis, emphasizing the need for extended patient follow-up.
Area of Science:
- Oncology
- Pathology
Background:
- Epithelial-myoepithelial carcinoma (EMC) is a rare, low-grade malignant salivary gland tumor.
- EMC exhibits low metastatic potential but a high local recurrence rate (~50%).
- Limited data exists for established treatment and follow-up guidelines due to its rarity.
Observation:
- An 83-year-old male presented with left submandibular swelling 9 years post-diagnosis of parotid gland EMC.
- Radiological and biopsy findings confirmed recurrence/metastasis of low-grade EMC.
Findings:
- This is the first reported case of loco-regional lymph node metastasis occurring 9 years after initial parotid gland EMC diagnosis.
- The case demonstrates a delayed metastatic presentation of EMC.
Implications:
- EMC of the parotid gland necessitates a prolonged follow-up period, even with early-stage diagnosis.
- This case underscores the importance of vigilant long-term monitoring for potential late recurrences or metastases.
- Further research is needed to establish optimal surveillance strategies for EMC patients.
