Identification of intraocular tumors by specular microscopy

Five patients with confirmed diagnoses of intraocular tumors and anterior chamber extension were examined with a wide-field specular microscope. Uniquely shaped dark areas seen on the endothelial surface could be readily distinguished from inflammatory cells by their size and shape. These structures were often associated with a surrounding bright reflection similar to that produced by pigment. The cellular morphology provided by specular microscopy offers the potential for differentiating neoplastic from inflammatory processes in the anterior chamber.