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[Influence of TRH on the depressive syndrome (author's transl)]
Abstract:
In two cases of chronic endogenous depression changes of mood and drive have been investigated over a period of 26 days by self rating scales "ESTA". After a single dose of 250 microgramm TRH a small antidepressive effect and a clear shift of the syndrome in the direction of a mixed state could be demonstrated thus suggesting an increased desintegration of the mood-drive-system.