Change in Ocular Tear Film After Entropion Repair Surgery in Involutional Entropion

Area of Science:

• Ophthalmology
• Ocular Surface Disease
• Surgical Outcomes

Background:

• Involutional entropion, a condition causing eyelid inversion, is associated with ocular surface abnormalities.
• Tear film dysfunction, including reduced lipid layer thickness (LLT) and meibomian gland dysfunction (MGD), is often observed in patients with entropion.

Purpose of the Study:

• To quantitatively assess the impact of corrective surgery for involutional entropion on key tear film parameters.
• To evaluate changes in lipid layer thickness (LLT), meibomian gland dysfunction (MGD), and incomplete blinking (IB) after surgical correction.

Main Methods:

• Retrospective analysis of 24 patients (48 eyes) with involutional entropion.
• Pre- and postoperative measurements of LLT, MGD grade, blinking patterns, Schirmer test, tear break-up time (BUT), and best-corrected visual acuity (BCVA) using LipiView II Ocular Surface Interferometer and meibography.

Main Results:

• Surgical correction led to a significant increase in LLT (66.74 nm to 81.37 nm) and improvement in MGD grade (1.60 to 1.29).
• Best-corrected visual acuity (BCVA) also showed significant improvement (P=0.047).
• No significant changes were noted in blinking rate, Schirmer score, or BUT.

Conclusions:

• Involutional entropion negatively impacts tear film LLT and MGD.
• Surgical correction of involutional entropion effectively improves LLT, MGD, and visual acuity.
• Entropion repair plays a crucial role in restoring ocular surface health and may benefit patients with meibomian gland-related tear film issues.